particle physics - Is it possible to destroy proton in proton-proton collision?

Or in proton-electron collision.

To destroy is to turn into other particles, not baryons. In context of the baryon asymmetry.

Answer

The way you used baryon made me wonder if you are unaware of the baryon nearly conservation law.

From the link:

The baryon number is nearly conserved in all the interactions of the Standard Model. 'Conserved' means that the sum of the baryon number of all incoming particles is the same as the sum of the baryon numbers of all particles resulting from the reaction. An exception is the chiral anomaly. However, sphalerons are not all that common. Electroweak sphalerons can only change the baryon number by 3.